A packet of envelopes <a href="http://www.mundotrundle.com/medicalcenterhowardcountycom-0ab5.pdf">cosmed.sk</a> After 16 months on the drug, patients who remained on the drug saw significant improvements on some tests of memory and problem solving. The drug appeared to work especially well in patients who carried a gene called APOE4, which confers the highest genetic risk for Alzheimer's. APOE4 carriers saw improvements in test scores that were about one-third to one-fourth higher than before they started the study.