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</a> Onyx, based in San Francisco, is such a cancer biotech. Two of its cancer therapies, Nexavar and Stivarga, are joined with with German drug maker Bayer AG. Onyx&#8217;s crown jewel is Kyprolis, a blood-cancer treatment approved in the U.S. last year. Onyx doesn&#8217;t release revenue details for Kyprolis. Last year, Onyx notched $362 million in sales.